Enhancement of colorectal tumor targeting using a novel biparatopic monoclonal antibody against carcinoembryonic antigen in experimental radioimmunoguided surgery.

Biparatopic CEA, carcinoembryonic antigen (MAb) was newly designed and tested as to whether it enhanced the accuracy of tumor detection by reducing non-specific binding in experimental radioimmunoguided surgery. Biparatopic MAb was prepared by using cross-linking of reduced Fab' fragments from...

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Bibliographic Details
Main Authors: Kim, J, Roh, SA, Koo, K, Ryu, J, Hong, H, Oh, S, Kim, H, Bodmer, W
Format: Journal article
Language:English
Published: 2002