Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle

DNA translesion synthesis (TLS) is a crucial damage tolerance pathway that oversees the completion of DNA replication in the presence of DNA damage. TLS polymerases are capable of bypassing a distorted template but they are generally considered inaccurate and they need to be tightly regulated. We ha...

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Bibliographic Details
Main Authors: Bertoletti, F, Cea, V, Liang, C, Lanati, T, Maffia, A, Avarello, M, Cipolla, L, Lehmann, A, Cohn, M, Sabbioneda, S
Format: Journal article
Published: Oxford University Press 2017