Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle
DNA translesion synthesis (TLS) is a crucial damage tolerance pathway that oversees the completion of DNA replication in the presence of DNA damage. TLS polymerases are capable of bypassing a distorted template but they are generally considered inaccurate and they need to be tightly regulated. We ha...
Main Authors: | Bertoletti, F, Cea, V, Liang, C, Lanati, T, Maffia, A, Avarello, M, Cipolla, L, Lehmann, A, Cohn, M, Sabbioneda, S |
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Format: | Journal article |
Published: |
Oxford University Press
2017
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