Pyrrolidinones derived from (S)-pyroglutamic acid. Part 4. alpha,beta-diaminopyrrolidinones
The electrophilic amination of a β-aminolactam, itself derived from the conjugate addition of O,N-dibenzyl-hydroxylamine to a highly activated α, β-unsaturated bicyclic lactam, provides direct access to conformationally constrained diamines. Sequential deprotection allows the synthesis of 3,4-diamin...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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