General pyrrolidine synthesis via iridium-catalyzed reductive azomethine ylide generation from tertiary amides and lactams

An iridium-catalyzed reductive generation of both stabilized and unstabilized azomethine ylides and their application to functionalized pyrrolidine synthesis via [3 + 2] dipolar cycloaddition reactions is described. Proceeding under mild reaction conditions from both amide and lactam precursors poss...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Yamazaki, K, Gabriel, P, Di Carmine, G, Pedroni, J, Farizyan, M, Hamlin, TA, Dixon, DJ
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: American Chemical Society 2021