JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors

Colorectal cancer (CRC) is a heterogenous malignancy underpinned by dysregulation of cellular signaling pathways. Previous literature has implicated aberrant JAK/STAT3 signal transduction in the development and progression of solid tumors. In this study we investigate the effectiveness of inhibiting...

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Bibliographic Details
Main Authors:	Pennel, KAF, Hatthakarnkul, P, Wood, CS, Lian, G, Al-Badran, SSF, Quinn, JA, Legrini, A, Inthagard, J, Alexander, PG, van Wyk, H, Kurniawan, A, Hashmi, U, Gillespie, MA, Mills, M, Ammar, A, Hay, J, Andersen, D, Nixon, C, Rebus, S, Chang, DK, Kelly, C, Harkin, A, Graham, J, Church, D
Format:	Journal article
Language:	English
Published:	BioMed Central 2024

JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors

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