The C-terminal rod 2 fragment of filamin A forms a compact structure that can be extended.

Filamins are large proteins that cross-link actin filaments and connect to other cellular components. The C-terminal rod 2 region of FLNa (filamin A) mediates dimerization and interacts with several transmembrane receptors and intracellular signalling adaptors. SAXS (small-angle X-ray scattering) ex...

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Bibliographic Details
Main Authors: Ruskamo, S, Gilbert, R, Hofmann, G, Jiang, P, Campbell, I, Ylänne, J, Pentikäinen, U
Format: Journal article
Language:English
Published: 2012