Genome-wide analysis of the hypoxic breast cancer transcriptome using next generation sequencing

<p>Hypoxia pathways are associated with the pathogenesis of both ischaemic and neoplastic diseases. In response to hypoxia the transcription factor hypoxia‐inducible factor (HIF) induces the expression of hundreds of genes with diverse functions. These enable cells to adapt to low oxygen avai...

Full description

Bibliographic Details
Main Author: Choudhry, H
Other Authors: Harris, A
Format: Thesis
Language:English
Published: 2014
Subjects: