Ex vivo expansion and genetic manipulation of mouse hematopoietic stem cells in polyvinyl alcohol-based cultures

Self-renewing multipotent hematopoietic stem cells (HSCs) are an important cell type due to their abilities to support hematopoiesis throughout life and reconstitute the entire blood system following transplantation. HSCs are used clinically in stem cell transplantation therapies, which represent cu...

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Bibliographic Details
Main Authors: Khoo, HM, Meaker, GA, Wilkinson, AC
Format: Journal article
Language:English
Published: MyJove Corporation 2023