ENANTIOSPECIFIC SYNTHESIS OF SWAINSONINE, (1S, 2R, 8R, 8AR)-1,2,8-TRIHYDROXYOCTAHYDROINDOLIZINE, FROM D-MANNOSE

An enantiospecific synthesis of swainsonine from D-mannose is described; the heterocyclic rings of swainsonine are constructed by two intramolecular reductive aminations caused by the catalytic hydrogenation of an azidoaldehyde with 5 equivalents of hydrogen. © 1984.

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Fleet, G, Gough, M, Smith, P
التنسيق: Journal article
اللغة:English
منشور في: 1984