Evidence from a large U.K. family collection that genes influencing age of onset of type 2 diabetes map to chromosome 12p and to the MODY3/NIDDM2 locus on 12q24.

Additional information on genetic susceptibility effects relevant to type 2 diabetes pathogenesis can be extracted from existing genome scans by extending examination to related phenotypes such as age at disease onset. In this study, we report the reanalysis of data from 573 U.K. sibships ascertaine...

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Bibliographic Details
Main Authors: Wiltshire, S, Frayling, T, Groves, C, Levy, J, Hitman, G, Sampson, M, Walker, M, Menzel, S, Hattersley, A, Cardon, L, McCarthy, M
Format: Journal article
Language:English
Published: 2004