Characterising the cellular and molecular basis of age-related clonal haematopoiesis

<p>Throughout life, tissue stem cells accumulate somatic mutations. Occasionally, a mutation may occur that confers a selective advantage leading to growth of an expanded clone. When this occurs in haematopoietic stem cells (HSC), this is called clonal haematopoiesis. Clonal haematopoiesis is...

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Bibliographic Details
Main Author: Jakobsen, NA
Other Authors: Vyas, P
Format: Thesis
Language:English
Published: 2022
Subjects: