The relationship between RTS,S vaccine-induced antibodies, CD4⁺ T cell responses and protection against Plasmodium falciparum infection

Vaccination with the pre-erythrocytic malaria vaccine RTS,S induces high levels of antibodies and CD4(+) T cells specific for the circumsporozoite protein (CSP). Using a biologically-motivated mathematical model of sporozoite infection fitted to data from malaria-naive adults vaccinated with RTS,S a...

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Manylion Llyfryddiaeth
Prif Awduron: White, M, Bejon, P, Olotu, A, Griffin, J, Riley, E, Kester, K, Ockenhouse, C, Ghani, A
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Public Library of Science 2013