An approach to the generation of simple analogues of the antitumour agent spicamycin.

The one-step glycosylation of arylamines in acidic medium is extended to adenine derivatives for the first time, providing a considerable improvement over existing reactions. This method is used to prepare some rhamnospicamycin analogues containing different base moieties. Results suggest that this...

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Bibliographic Details
Main Authors: Mons, S, Fleet, G
Format: Journal article
Language:English
Published: 2003