Toward a quantitative understanding of the Wnt/beta-catenin pathway through simulation and experiment
Wnt signaling regulates cell survival, proliferation, and differentiation throughout development and is aberrantly regulated in cancer. The pathway is activated when Wnt ligands bind to specific receptors on the cell surface, resulting in the stabilization and nuclear accumulation of the transcripti...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Published: |
Wiley
2013
|