Structure-activity studies reveal scope for optimisation of Ebselen-type inhibition of SARS-COV-2 main protease

<p>The reactive organoselenium compound ebselen is being investigated for treatment of coronavirus disease 2019 (COVID-19) and other diseases. We report structure-activity studies on sulfur analogues of ebselen with the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) main protease...

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Bibliographic Details
Main Authors: Thun-Hohenstein, STD, Suits, TF, Malla, TR, Tumber, A, Brewitz, L, Choudhry, H, Salah, E, Schofield, CJ
Format: Journal article
Language:English
Published: Wiley 2021