Enzyme-less DNA base identification by chemical stepping in a nanopore

The stepwise movement of a single biopolymer strand through a nanoscopic detector for the sequential identification of its building blocks offers a universal means for single-molecule sequencing. This principle has been implemented in portable sequencers that use enzymes to move DNA or RNA through h...

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Bibliographic Details
Main Authors: Qing, Y, Bayley, H
Format: Journal article
Language:English
Published: American Chemical Society 2021