Enzyme-less DNA base identification by chemical stepping in a nanopore

Enzyme-less DNA base identification by chemical stepping in a nanopore

The stepwise movement of a single biopolymer strand through a nanoscopic detector for the sequential identification of its building blocks offers a universal means for single-molecule sequencing. This principle has been implemented in portable sequencers that use enzymes to move DNA or RNA through h...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Qing, Y, Bayley, H
Natura:	Journal article
Lingua:	English
Pubblicazione:	American Chemical Society 2021

Documenti analoghi

Enzyme-less nanopore detection of post-translational modifications within long polypeptides
di: Martin-Baniandres, P, et al.
Pubblicazione: (2023)

Continuous base identification for single-molecule nanopore DNA sequencing
di: Clarke, J, et al.
Pubblicazione: (2009)

Continuous base identification for single-molecule nanopore DNA sequencing.
di: Clarke, J, et al.
Pubblicazione: (2009)

Identification of epigenetic DNA modifications with a protein nanopore.
di: Wallace, E, et al.
Pubblicazione: (2010)

Single-molecule detection of 5-hydroxymethylcytosine in DNA through chemical modification and nanopore analysis.
di: Li, W, et al.
Pubblicazione: (2013)

DNA scaffolds support stable and uniform peptide nanopores
di: Spruijt, E, et al.
Pubblicazione: (2018)

Are we there yet?: Comment on "Nanopores: A journey towards DNA sequencing" by Meni Wanunu.
di: Bayley, H
Pubblicazione: (2012)

Are we there yet?. Comment on "Nanopores: A journey towards DNA sequencing" by Meni Wanunu.
di: Bayley, H
Pubblicazione: (2012)

Single-nucleotide discrimination in immobilized DNA oligonucleotides with a biological nanopore.
di: Stoddart, D, et al.
Pubblicazione: (2009)

Controlled translocation of individual DNA molecules through protein nanopores with engineered molecular brakes.
di: Rincon-Restrepo, M, et al.
Pubblicazione: (2011)

Nucleobase recognition at alkaline pH and apparent pKa of single DNA bases immobilised within a biological nanopore.
di: Franceschini, L, et al.
Pubblicazione: (2012)

Urea facilitates the translocation of single-stranded DNA and RNA through the alpha-hemolysin nanopore.
di: Japrung, D, et al.
Pubblicazione: (2010)

Enhanced translocation of single DNA molecules through alpha-hemolysin nanopores by manipulation of internal charge.
di: Maglia, G, et al.
Pubblicazione: (2008)

Electrochemical DNA biosensor based on nanoporous alumina membrane
di: Deng, Jiajia
Pubblicazione: (2014)

Local electrical potential detection of DNA by nanowire–nanopore sensors
di: Lieber, Charles M., et al.
Pubblicazione: (2013)

Individual RNA base recognition in immobilized oligonucleotides using a protein nanopore.
di: Ayub, M, et al.
Pubblicazione: (2012)

Molecular dynamics simulations of DNA within a nanopore: arginine-phosphate tethering and a binding/sliding mechanism for translocation.
di: Bond, P, et al.
Pubblicazione: (2011)

Protein nanopores with covalently attached molecular adapters.
di: Wu, H, et al.
Pubblicazione: (2007)

Simulations and Modelling of Biomimetic Nanopores
di: Trick, J, et al.
Pubblicazione: (2013)

Protein detection by nanopores equipped with aptamers.
di: Rotem, D, et al.
Pubblicazione: (2012)

Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
di: Banerjee, A, et al.
Pubblicazione: (2010)

DNA strands from denatured duplexes are translocated through engineered protein nanopores at alkaline pH.
di: Maglia, G, et al.
Pubblicazione: (2009)

Multistep protein unfolding during nanopore translocation.
di: Rodriguez-Larrea, D, et al.
Pubblicazione: (2013)

DNA Knot Malleability in Single-Digit Nanopores
di: Sharma, Rajesh Kumar, et al.
Pubblicazione: (2021)

Multistep protein unfolding during nanopore translocation
di: Rodriguez-Larrea, D, et al.
Pubblicazione: (2013)

DNA nanopores as artificial membrane channels for bioprotonics
di: Luo, Le, et al.
Pubblicazione: (2023)

Nanopore unstacking of single-stranded DNA helices
di: Chen, Peng, et al.
Pubblicazione: (2012)

Stability and Dynamics of Membrane-Spanning DNA Nanopores
di: Maingi, V, et al.
Pubblicazione: (2017)

Complex DNA knots detected with a nanopore sensor
di: Doyle, Patrick S.
Pubblicazione: (2020)

Phonon bottleneck identification in disordered nanoporous materials
di: Romano, Giuseppe, et al.
Pubblicazione: (2017)

Single-molecule protein phosphorylation and dephosphorylation by nanopore enzymology
di: Harrington, L, et al.
Pubblicazione: (2018)

Real-time stochastic detection of multiple neurotransmitters with a protein nanopore.
di: Boersma, A, et al.
Pubblicazione: (2012)

Single-molecule detection of nitrogen mustards by covalent reaction within a protein nanopore.
di: Wu, H, et al.
Pubblicazione: (2008)

Continuous stochastic detection of amino acid enantiomers with a protein nanopore.
di: Boersma, A, et al.
Pubblicazione: (2012)

Cleavage of fragments containing DNA mismatches by enzymic and chemical probes.
di: Brown, J, et al.
Pubblicazione: (2003)

Translocating kilobase RNA through the Staphylococcal α-hemolysin nanopore.
di: Cracknell, J, et al.
Pubblicazione: (2013)

NO LESS SUPER - THE NEXT STEP FOR EUROPE PARTICLE PHYSICS
di: Foster, B
Pubblicazione: (1994)

Electroactive Nanoporous Metal Oxides and Chalcogenides by Chemical Design
di: Hendon, Christopher H, et al.
Pubblicazione: (2020)

Multiple base-recognition sites in a biological nanopore: two heads are better than one.
di: Stoddart, D, et al.
Pubblicazione: (2010)

Nanoporous carbon as a sensing platform for DNA detection : the use of impedance spectroscopy for hairpin-DNA based assay
di: Poh, Hwee Ling, et al.
Pubblicazione: (2013)