HLA-associated polymorphisms in the HIV-2 capsid highlight key differences between HIV-1 and HIV-2 immune adaptation

<p><b>Objective:</b> HIV-1 frequently adapts in response to immune pressure from cytotoxic T-lymphocytes (CTL). Many HIV-2 infected individuals have robust capsid-specific CTL responses associated with viral control. Despite this CTL pressure, adaptive changes in this key immunoge...

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Bibliographic Details
Main Authors: de Silva, T, Leligdowicz, A, Carlson, J, Garcia-Knight, M, Onyango, C, Miller, N, Yindom, L, Hué, S, Jaye, A, Dong, T, Cotten, M, Rowland-Jones, S
Format: Journal article
Language:English
Published: Lippincott, Williams & Wilkins 2018