Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu.

It is generally accepted that human Alzheimer's disease (AD) neuropathology markers are completely absent in rodent brains. We report here that an aged wild-type South American rodent, Octodon degu, expresses neuronal beta-amyloid precursor protein (beta-APP695) displaying both intracellular an...

Full description

Bibliographic Details
Main Authors: Inestrosa, N, Reyes, A, Chacón, M, Cerpa, W, Villalón, A, Montiel, J, Merabachvili, G, Aldunate, R, Bozinovic, F, Aboitiz, F
Format: Journal article
Language:English
Published: 2005