In vivo pretargeted imaging of HER2 and TAG-72 expression using the HaloTag enzyme

A novel pretargeted SPECT imaging strategy based on the HaloTag enzyme has been evaluated for the first time in a living system. To determine the efficacy of this approach, two clinically relevant cancer biomarkers, HER2 and TAG-72, were selected to represent models of internalizing and non-internal...

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Bibliographic Details
Main Authors: Knight, J, Mosley, M, Uyeda, T, Cong, M, Fan, F, Faulkner, S, Cornelissen, B
Format: Journal article
Published: American Chemical Society 2017