Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?

There is increasing evidence that NF-kappaB is a major, if not the major transcription factor regulating inflammation and immunity. While this implies that blocking NF-kappaB might be therapeutically beneficial, it raises clear questions regarding the balance between efficacy and safety. In this bri...

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Bibliographic Details
Main Authors: Feldmann, M, Andreakos, E, Smith, C, Bondeson, J, Yoshimura, S, Kiriakidis, S, Monaco, C, Gasparini, C, Sacre, S, Lundberg, A, Paleolog, E, Horwood, N, Brennan, F, Foxwell, B
Format: Journal article
Language:English
Published: 2002