Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function.

Variability in expression of the 5-HT transporter (5-HTT) gene in the human population has been associated with a range of behavioural phenotypes. The underlying mechanisms are unclear but may involve changes in 5-HT receptor levels and/or signalling. The present study used a novel 5-HTT overexpress...

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Autori principali: Jennings, K, Sheward, W, Harmar, A, Sharp, T
Natura: Journal article
Lingua:English
Pubblicazione: 2008