A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases.
Penicillin binding proteins (PBPs) and β-lactamases are involved in interactions with β-lactam antibiotics connected with both antibacterial activity and mediation of bacterial β-lactam resistance. Current methods for identifying inhibitors of PBPs and β-lactamases can be inefficient and are often n...
Main Authors: | , , , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado: |
2012
|