A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases.

Penicillin binding proteins (PBPs) and β-lactamases are involved in interactions with β-lactam antibiotics connected with both antibacterial activity and mediation of bacterial β-lactam resistance. Current methods for identifying inhibitors of PBPs and β-lactamases can be inefficient and are often n...

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Detalles Bibliográficos
Main Authors: Inglis, SR, Strieker, M, Rydzik, A, Dessen, A, Schofield, C
Formato: Journal article
Idioma:English
Publicado: 2012