Cytosolic processing governs TAP-independent presentation of a critical melanoma antigen

Cancer immunotherapy has been flourishing in recent years with remarkable clinical success. But as more patients are treated, a shadow is emerging that has haunted other cancer therapies: tumors develop resistance. Resistance is often caused by defects in the MHC class I Ag presentation pathway crit...

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Bibliographic Details
Main Authors: Vigneron, N, Ferrari, V, Van Den Eynde, B, Cresswell, P, Leonhardt, R
Format: Journal article
Language:English
Published: American Association of Immunologists 2018