Minimal models for cell-cycle control based on competitive inhibition and multisite phosphorylations of Cdk substrates.

The eukaryotic cell cycle is characterized by alternating oscillations in the activities of cyclin-dependent kinase (Cdk) and the anaphase-promoting complex (APC). Successful completion of the cell cycle is dependent on the precise, temporally ordered appearance of these activities. A modest level o...

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Bibliographic Details
Main Authors: Gérard, C, Tyson, J, Novák, B
Format: Journal article
Language:English
Published: 2013