Timing of galectin-1 exposure differentially modulates Nipah virus entry and syncytium formation in endothelial cells.

Nipah virus (NiV) is a deadly emerging enveloped paramyxovirus that primarily targets human endothelial cells. Endothelial cells express the innate immune effector galectin-1 that we have previously shown can bind to specific N-glycans on the NiV envelope fusion glycoprotein (F). NiV-F mediates fusi...

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Bibliographic Details
Main Authors: Garner, O, Yun, T, Pernet, O, Aguilar, H, Park, A, Bowden, T, Freiberg, A, Lee, B, Baum, L
Format: Journal article
Language:English
Published: 2015