High-resolution crystal structure of arthropod Eiger TNF suggests a mode of receptor engagement and altered surface charge within endosomes

<p>The tumour necrosis factor alpha (TNFα) superfamily of proteins are critical in numerous biological processes, such as in development and immunity. Eiger is the sole TNFα member described in arthropods such as in the important model organism <em>Drosophila</em>. To date there ar...

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Bibliographic Details
Main Authors: Bertinelli, M, Paesen, G, Grimes, J, Renner, M
Format: Journal article
Language:English
Published: Nature Research 2019