T cell tolerance in transplantation: possibilities for therapeutic intervention.

It is now possible to induce donor-specific transplantation tolerance in adult rodents using a number of therapeutic strategies. These include the use of non-depleting monoclonal antibodies against T cell co-receptor and costimulation molecules, and immunisation with tolerogenic antigen-presenting c...

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Bibliographic Details
Main Author: Cobbold, S
Format: Journal article
Language:English
Published: 2002