Exosomes for targeted siRNA delivery across biological barriers

Using oligonucleotide-based drugs to modulate gene expression has opened a new avenue for drug discovery. In particular small interfering RNAs (siRNAs) are being rapidly recognized as promising therapeutic tools, but their poor bioavailability limits the full realization of their clinical potential....

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Bibliographic Details
Main Authors: Andaloussi, S, Lakhal, S, Mäger, I, Wood, M
Format: Journal article
Published: 2013