Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer.

The cationic lipid GL67A is one of the more efficient non-viral gene transfer agents (GTAs) for the lungs, and is currently being evaluated in an extensive clinical trial programme for cystic fibrosis gene therapy. Despite conferring significant expression of vector-specific mRNA following transfect...

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Bibliographic Details
Main Authors: Griesenbach, U, Vicente, C, Roberts, M, Meng, C, Soussi, S, Xenariou, S, Tennant, P, Baker, A, Baker, E, Gordon, C, Vrettou, C, McCormick, D, Coles, R, Green, A, Lawton, A, Sumner-Jones, S, Cheng, S, Scheule, R, Hyde, S, Gill, DR, Collie, D, McLachlan, G, Alton, E
Format: Journal article
Language:English
Published: 2011