Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila.

Various inhibitors of metallo-beta-lactamases have been reported; however, none are effective for all subgroups. Those that have been found to inhibit the enzymes of subclass B2 (catalytically active with one zinc) either contain a thiol (and show less inhibition towards this subgroup than towards t...

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Bibliographic Details
Main Authors: Horsfall, L, Garau, G, Liénard, B, Dideberg, O, Schofield, C, Frère, J, Galleni, M
Format: Journal article
Language:English
Published: 2007