In vivo characterization of 123/125I-2-iodo-L-phenylalanine in an R1M rhabdomyosarcoma athymic mouse model as a potential tumor tracer for SPECT.

UNLABELLED: The application of 123I-3-iodo-alpha-methyltyrosine is limited to diagnosis of brain tumors due to its marked long-term uptake in kidneys. In vitro evaluation of 125I-2-iodo-L-phenylalanine showed high uptake in R1M cells by L-type amino acid transport system 1 (LAT1). This study evalua...

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Bibliographic Details
Main Authors: Kersemans, V, Cornelissen, B, Kersemans, K, Bauwens, M, Achten, E, Dierckx, R, Mertens, J, Slegers, G
Format: Journal article
Language:English
Published: 2005