Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a devastating neurodegenerative disorder characterized by the progressive loss of spinal motor neurons. While the aetiological mechanisms underlying the disease remain poorly understood, oxidative stress is a central component of amyotrophic lateral sclerosis and con...

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Bibliographic Details
Main Authors: Liu, K, Edwards, B, Lee, S, Finelli, M, Davies, B, Davies, K, Oliver, P
Format: Journal article
Language:English
Published: Oxford University Press 2015