Conserved TCR beta chain usage in reactive arthritis; evidence for selection by a putative HLA-B27-associated autoantigen.

Conserved TCR beta chain usage in reactive arthritis; evidence for selection by a putative HLA-B27-associated autoantigen.

Previous work suggested that expanded CD8+ T-cell clones in the synovial fluid (SF) of HLA-B27+ patients with reactive arthritis (ReA) preferentially use the T-cell receptor variable region (TCRBV) 1, similar CDR3 sequences, and joining region (BJ) 2S3. To determine the range of conservation and dis...

书目详细资料
Main Authors:	May, E, Dulphy, N, Frauendorf, E, Duchmann, R, Bowness, P, Lopez de Castro, J, Toubert, A, Märker-Hermann, E
格式:	Journal article
语言:	English
出版:	2002

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