Condition-dependent generation of aquaporin-4 antibodies from circulating B cells in neuromyelitis optica
Autoantibodies to aquaporin-4 (AQP4) are pathogenic in neuromyelitis optica spectrum disorder (NMOSD). However, it is not known which B cells are the major contributors to circulating AQP4 antibodies nor which conditions promote their generation. Our experiments showed CD19+CD27++CD38++ circulating...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Oxford University Press
2018
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