The importance of Ca(2+)-dependent mechanisms for the initiation of the heartbeat.
Mechanisms underlying pacemaker activity in the sinus node remain controversial, with some ascribing a dominant role to timing events in the surface membrane ("membrane clock") and others to uptake and release of calcium from the sarcoplasmic reticulum (SR) ("calcium clock"). Her...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Frontiers
2015
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