Resistance of transmitted founder HIV-1 to IFITM-mediated restriction

Interferon-induced transmembrane proteins (IFITMs) restrict the entry of diverse enveloped viruses through incompletely understood mechanisms. While IFITMs are reported to inhibit HIV-1, their in vivo relevance is unclear. We show that IFITM sensitivity of HIV-1 strains is determined by the co-recep...

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Hlavní autoři: Foster, T, Wilson, H, Iyer, S, Coss, K, Doores, K, Smith, S, Kellam, P, Finzi, A, Borrow, P, Hahn, B, Neil, S
Médium: Journal article
Jazyk:English
Vydáno: Cell Press 2016