A spatially-averaged mathematical model of kidney branching morphogenesis.

Kidney development is initiated by the outgrowth of an epithelial ureteric bud into a population of mesenchymal cells. Reciprocal morphogenetic responses between these two populations generate a highly branched epithelial ureteric tree with the mesenchyme differentiating into nephrons, the functiona...

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Bibliographic Details
Main Authors: Zubkov, V, Combes, A, Short, K, Lefevre, J, Hamilton, N, Smyth, I, Little, M, Byrne, H
Format: Journal article
Language:English
Published: Elsevier 2015