A mass action model of a Fibroblast Growth Factor signaling pathway and its simplification.
We consider a kinetic law of mass action model for Fibroblast Growth Factor (FGF) signaling, focusing on the induction of the RAS-MAP kinase pathway via GRB2 binding. Our biologically simple model suffers a combinatorial explosion in the number of differential equations required to simulate the syst...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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