Nur77 controls tolerance induction, terminal differentiation, and effector functions in NKT cells
Natural killer T (NKT) cells are self-reactive lymphocytes, yet how this lineage attains self-tolerance remains unknown. NKT cells constitutively express high levels of Nr4a1-encoded Nur77, a transcription factor that integrates signal strength downstream of the T cell receptor (TCR) within activate...
| Main Authors: | , , , , , , , , |
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| Format: | Conference item |
| Language: | English |
| Published: |
American Association of Immunologists
2020
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