Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate.

OBJECTIVES: To investigate baricitinib (LY3009104, formerly INCB028050), a novel, oral inhibitor of JAK1/JAK2 in patients with moderate to severe rheumatoid arthritis (RA) despite treatment with methotrexate. METHODS: In this phase IIb study, 301 patients were randomised 2:1:1:1:1 to receive once da...

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Détails bibliographiques
Auteurs principaux: Keystone, E, Taylor, P, Drescher, E, Schlichting, D, Beattie, S, Berclaz, P, Lee, C, Fidelus-Gort, R, Luchi, M, Rooney, T, Macias, W, Genovese, M
Format: Journal article
Langue:English
Publié: 2015