Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

Prior studies have demonstrated that immunologic dysfunction underpins severe illness in COVID-19 patients, but have lacked an in-depth analysis of the immunologic drivers of death in the most critically ill patients. We performed immunophenotyping of viral antigen-specific and unconventional T cell...

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Bibliographic Details
Main Authors:	Youngs, J, Provine, NM, Lim, N, Sharpe, HR, Amini, A, Chen, Y-L, Luo, J, Edmans, MD, Zacharopoulou, P, Chen, W, Sampson, O, Paton, R, Hurt, WJ, Duncan, DA, McNaughton, AL, Miao, VN, Leaver, S, Wyncoll, DLA, Ball, J, Hopkins, P, Oxford Protective T cell Immunology for COVID-19 (OPTIC) Clinical team, Skelly, DT, Barnes, E, Dunachie, S, Ogg, G, Lambe, T, Pavord, I, Shalek, AK, Thompson, CP, Xue, L, Macallan, DC, Goulder, P, Klenerman, P, Bicanic, T
Other Authors:	Oxford Immunology Network Covid-19 response T cell Consortium
Format:	Journal article
Language:	English
Published:	Public Library of Science 2021

Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

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