Topological defects in epithelia govern cell death and extrusion

Epithelial tissues (epithelia) remove excess cells through extrusion, preventing the accumulation of unnecessary or pathological cells. The extrusion process can be triggered by apoptotic signalling1, oncogenic transformation2, 3 and overcrowding of cells4, 5, 6. Despite the important linkage of cel...

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Bibliographic Details
Main Authors: Saw, T, Doostmohammadi, A, Nier, V, Kocgozlu, L, Thampi, S, Toyama, Y, Marcq, P, Lim, C, Yeomans, J, Ladoux, B
Format: Journal article
Published: Nature Publishing Group 2017