Identifying small-effect genetic associations overlooked by the conventional fixed-effect model in a large-scale meta-analysis of coronary artery disease
<p><strong>Motivation:</strong><br/> Common small-effect genetic variants that contribute to human complex traits and disease are typically identified using traditional fixed-effect meta-analysis methods. However, the power to detect genetic associations under fixed-effect mo...
Hlavní autoři: | Magosi, LE, Goel, A, Hopewell, JC, Farrall, M |
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Další autoři: | The Cardiogramplusc4D Consortium |
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
Oxford University Press
2019
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