Imaging plasma membrane phase behaviour in live cells using a thiophene-based molecular rotor.

Molecular rotors have emerged as versatile probes of microscopic viscosity in lipid bilayers, although it has proved difficult to find probes that stain both phases equally in phase-separated bilayers. Here, we investigate the use of a membrane-targeting viscosity-sensitive fluorophore based on a th...

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Bibliographic Details
Main Authors: Dent, M, López-Duarte, I, Dickson, C, Chairatana, P, Anderson, H, Gould, I, Wylie, D, Vyšniauskas, A, Brooks, N, Kuimova, M
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2016