Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection

Objectives Malaria, caused by Plasmodium infection, remains a major global health problem. Monocytes are integral to the immune response, yet their transcriptional and functional responses in primary Plasmodium falciparum infection and in clinical malaria are poorly understood. Methods The transcri...

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Bibliographic Details
Main Authors: Loughland, JR, Woodberry, T, Field, M, Andrew, DW, SheelaNair, A, Dooley, NL, Piera, KA, Amante, FH, Kenangalem, E, Price, RN, Engwerda, CR, Anstey, NM, McCarthy, JS, Boyle, MJ, Minigo, G
Format: Journal article
Language:English
Published: Nature Publishing Group 2020