Oligomerisation of pneumolysin on cholesterol crystals: similarities to the behaviour of polyene antibiotics.

Pneumolysin is a cytolytic toxin of Streptococcus pneumoniae, a causative agent of pneumonia and meningitis. The prepore and pore states of pneumolysin have recently been investigated by cryo-electron microscopy and atomic force microscopy, confirming the existence of arc-shaped as well as ring-form...

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Bibliographic Details
Main Authors: Sonnen, A, Rowe, A, Andrew, P, Gilbert, R
Format: Journal article
Language:English
Published: 2008