Oligomerisation of pneumolysin on cholesterol crystals: similarities to the behaviour of polyene antibiotics.
Pneumolysin is a cytolytic toxin of Streptococcus pneumoniae, a causative agent of pneumonia and meningitis. The prepore and pore states of pneumolysin have recently been investigated by cryo-electron microscopy and atomic force microscopy, confirming the existence of arc-shaped as well as ring-form...
Main Authors: | Sonnen, A, Rowe, A, Andrew, P, Gilbert, R |
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Format: | Journal article |
Language: | English |
Published: |
2008
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