Analysis of B cell repertoire dynamics following hepatitis B vaccination in humans, and enrichment of vaccine-specific antibody sequences

Generating a diverse B cell immunoglobulin repertoire is essential for protection against infection. The repertoire in humans can now be comprehensively measured by high-throughput sequencing. Using hepatitis B vaccination as a model, we determined how the total immunoglobulin sequence repertoire ch...

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Bibliographic Details
Main Authors: Galson, J, Trück, J, Fowler, A, Clutterbuck, E, Münz, M, Cerundolo, V, Reinhard, C, van der Most, R, Pollard, A, Lunter, G, Kelly, D
Format: Journal article
Language:English
Published: Elsevier 2015